Subclinical Myocardial Dysfunction in Metabolic Syndrome Patients without Hypertension.
10.4250/jcu.2011.19.3.134
- Author:
Jeong Min SEO
1
;
Tae Ho PARK
;
Dong Yeol LEE
;
Young Rak CHO
;
Hee Kyung BAEK
;
Jong Seong PARK
;
Moo Hyun KIM
;
Young Dae KIM
;
Sun Young CHOI
;
Sun Mi LEE
;
Young Seoub HONG
Author Information
1. Department of Cardiology, Dong-A University College of Medicine, Busan, Korea. thpark65@dau.ac.kr
- Publication Type:Original Article
- Keywords:
Metabolic syndrome;
Doppler echocardiography
- MeSH:
Blood Pressure;
Echocardiography;
Echocardiography, Doppler;
Humans;
Hypertension;
Sprains and Strains;
Waist Circumference
- From:Journal of Cardiovascular Ultrasound
2011;19(3):134-139
- CountryRepublic of Korea
- Language:English
-
Abstract:
BACKGROUND: The aim of this study was to evaluate myocardial function in patients with non-hypertensive metabolic syndrome. METHODS: We selected metabolic syndrome patients (n = 42) without evidence of hypertension and compared them to age-matched control individuals (n = 20). All patients were evaluated by two-dimensional and tissue Doppler echocardiography including tissue Doppler derived strain and strain rate measurements. RESULTS: There were no significant differences between the two groups in mitral E and A inflow velocities or the E/A ratio. However, systolic and early diastolic myocardial velocities, and strain rate were significantly lower in patients with metabolic syndrome than in the control group (all p < 0.05). Multiple stepwise regression analyses revealed that age, waist circumference, and systolic blood pressure were independently associated with peak systolic myocardial velocity. CONCLUSION: These results indicate that metabolic syndrome patients without hypertension may have decrease of myocardial systolic and early diastolic velocities on tissue Doppler imaging, even if they appear to have normal systolic and diastolic function on conventional echocardiography.
