Clinical effect of erythromycin and azithromycin in the treatment of pediatric mycoplasma pneumonia
10.13699/j.cnki.1001-6821.2015.08.001
- VernacularTitle:红霉素与阿奇霉素治疗小儿肺炎支原体肺炎的临床研究
- Author:
Jia-Hui CHEN
1
;
Gen-Quan YIN
;
Jia-Lu YU
;
Li DENG
Author Information
1. 广州市妇女儿童医疗中心 呼吸科
- Keywords:
erythromycin;
azithromycin;
mycoplasma pneumonia
- From:
The Chinese Journal of Clinical Pharmacology
2015;(8):587-589
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the clinical efficacy of erythromycin and azithromycin sequential therapy with single azithromycin treatment on pediatric mycoplasma pneumonia .Methods One hundred and fourteen cases of pediatric mycoplasma pneumonia were randomly divided into two groups, with 57 cases in each group.Patients in the treatment group were treated with erythromycin combined with azithromycin , and those in the control group were treated with azithromycin , and the treatment lasted for 3 weeks.The data of clinical efficacy , clinical symptoms and hospitaliza-tion time of two groups were compared after treatment . Results The total effective rate of the treatment group was 96.49%, significantly higher than that of control group ( 77.19%) ( P<0.01 ) . The time points that fever , cough and lung rales disappeared and hospi-talization time of the treatment group were significantly lower than those of control group ( P<0.01 ).The rate of adverse reactions in the treatment group was 7.02% and 3.51% in control group but without statistical difference ( P>0.05).Conclusion Erythromycin combined with azithro-mycin treatment for pediatric mycoplasma pneumonia is notably effective .
