Recent advances in ocular drug delivery systems
10.13699/j.cnki.1001-6821.2015.07.028
- VernacularTitle:眼科药物传递技术及其研究与发展概况
- Author:
Shan-Shan ZHANG
1
;
Jing ZHU
;
Yong-Yue ZHAO
;
Wei ZHANG
;
Zhen-Yu MIAO
;
Jian-Jun GUO
;
Hai-Zhi BU
Author Information
1. 苏州市眼科医院
- Keywords:
ocular;
drug delivery;
permeability;
bioavailability
- From:
The Chinese Journal of Clinical Pharmacology
2015;(7):580-583
- CountryChina
- Language:Chinese
-
Abstract:
The eye is a highly protected organ , which makes it a formida-ble task to develop an effective drug delivery approach for ocular disea-ses.Transport of drugs applied by traditional dosage forms such as topical and intravitreal routes of administration is severely restricted to the eye , especially to the posterior segment areas.During the past decades , great progress has been made in ocular drug delivery systems facilitated by new technologies such as microemulsion , nanosuspension , nanoparticle , lipo-some, niosome, dendrimer, contact lens, intraocular implants, ionto-phoresis and microneedle , et al.In this review , recent developments of ocular drug delivery systems are summarized.
