Bibliometric analysis of antifungal effect of echinocandin on biofilm
10.13699/j.cnki.1001-6821.2015.04.019
- VernacularTitle:棘白菌素对真菌生物被膜作用的文献计量分析
- Author:
Xiu-Zhen DI
1
;
Nan BAI
;
Ming-Jing TANG
;
Yan BAI
;
Ke WEN
;
Hui NIU
;
Sheng ZHANG
;
Rui WANG
;
Jin WANG
Author Information
1. 解放军总医院 转化医学中心 药物/器械临床试验中心
- Keywords:
echinocandin;
biofilm;
bibliographic study;
bibliometric analysis;
fugus
- From:
The Chinese Journal of Clinical Pharmacology
2015;(4):300-303
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the development of echinocandin research on fungal biofilm from international and domestic databases from 2001 to 2013.Methods All publications were searched on international and domestic databases ( SCI, PubMed, EmBase, CNKI and SinoMed) and were screened by Endnote X7 software, then analysis was performed according to the publication year, author, article types, literature source , times cited and research content.Results A total of 153 publi-cations ( most were research articles) including 148 international and 5 domestic papers were searched from databases.The highest citation fre-quency of the literature was 157 times.A total of 62 research articles focused on Candida albicans.Most were monotherapy of echinocandin for fugal biofilm. A total of 24 research articles focused on caspofungin affecting the biofilm of C.Albicans.Fourteen papers concentrated on echinocandin combinations and few papers involved clinical research ( three papers ) .Conclusion The monotherapy of echinocandin can inhibit fugal biofilm, but combinations were not ideal.Biofilm infection model in vivo is still one of the key research areas, as well as the transition from basic research to clinical research.
