Salmeterol/fluticasone propionate combined with bailing capsule in the treatment of acute chronic obstructive pulmonary disease
10.13699/j.cnki.1001-6821.2015.04.002
- VernacularTitle:沙美特罗/丙酸氟替卡松联合百令胶囊治疗慢性阻塞性肺疾病的临床研究
- Author:
Cheng-Zhe SHU
1
;
Liang GU
Author Information
1. 上海市天山中医医院 药剂科
- Keywords:
stable period;
chronic obstructive pulmonary disease;
salmeterol/fluticasone propionate;
bailing capsule
- From:
The Chinese Journal of Clinical Pharmacology
2015;(4):247-249
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the clinical efficacy of salmeterol/fluticasone propionate combined with bailing capsule in the treatment of chronic obstructive pulmonary disease ( COPD).Methods Eighty cases with COPD were recruited in this study from Dec 2011 to Feb 2013.The included subjects were randomized divided into experiment group (n=38) and control group (n=42).Patients in experiment group were given salmeterol/fluticasone propionate (50 μg/100 μg) combined with bailing capsule 3 g? d-1 , while patients in the control group were given salme-terol/fluticasone propionate only.After 6 -month treatment, the data of forced expiratory volume in one second ( FEV1 ) , forced vital capacity(FVC), FEV1/FVC and 6 minutes walking test(6MWT) were recorded and compared between two groups. Results The data of FEV1, FVC, FEV1/FVC and 6MWT were all improved after 6-month treatment in the groups ( P <0.05 ) .The onset rate in the experiment group was much lower than that in the control group [ ( 2.8 ±1.9 ) vs (4.1 ±2.1), P<0.05], and the COPD stable period in the experiment group was much longer than that in the control group [(209.3 ±34.2) vs (47.2 ±54.3), P<0.05].Conclusion The salmeterol/fluticasone propionate combined with bailing capsule can significantly prevent the COPD patients from acute seizures, and the quality of life would be improved.
