Advance of the study on anesthesia and analgesia of pentazocine
10.13699/j.cnki.1001-6821.2015.02.024
- VernacularTitle:喷他佐辛用于麻醉和镇痛的临床研究进展
- Author:
Xiao-Xiao LI
1
;
Suo-Di ZHAI
Author Information
1. 北京大学第三医院药剂科
- Keywords:
pentazocine;
anesthesia;
acute pain;
chronic pain;
clinical research
- From:
The Chinese Journal of Clinical Pharmacology
2015;(2):158-160
- CountryChina
- Language:Chinese
-
Abstract:
This review collected the recent clinical application of pen-tazocine in preoperative anesthesia , acute pain and chronic pain.Data of pharmacodynamics , pharmacokinetics and safety evaluation related to pentazocine were retrieved and analyzed.Pentazocin can decrease the in-cidence of adverse drug reactions when as additional analgesics adminis-trated either before anesthesia or during anesthesia induction and main -tenance.The clinical efficacy of pentazocine in postoperative acute pain has been confirmed , with a low incidence of adverse reaction.Prolonged injection of pentazocine may cause drug dependence leading to lesions in skin and soft tissue.
