Anti-inflammatory, analgesic and strengthening Yang activities of ethanol extract from Eleutherine plicata
10.13699/j.cnki.1001-6821.2015.01.014
- VernacularTitle:红葱乙醇提取物的抗炎镇痛及壮阳作用
- Author:
Qing-Xi MIN
1
;
Pei-Fang WU
;
Quan-Hong ZHU
;
Hong-Xing WANG
Author Information
1. 南方医科大学 中医药学院
- Keywords:
Eleutherine plicata;
anti-inflammatory;
analgesia;
strengthe-ning Yang
- From:
The Chinese Journal of Clinical Pharmacology
2015;(1):44-47
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the anti-inflammatory, analgesic and strengthening Yang activities of ethanol extract from Eleutherine plicata ( EEEP) .Methods Mices or rats were divided into the blank group, positive control group, EEEP of the low -dose group, middle -dose group and high-dose group.The models of ear edema in mice, increa-sing blood capillary permeability of the skin induced by dimethylbenzene and the twist induced by acetic acid with administration for 4 days were used to study the inhibition ratio of ear edema, leakage of dye, writhing response.An model of normal male rats with administration for 7 days was used to study capture incubation period ( CIP) , capture times ( CT) and ejaculation times.Results Compared with blank group,high-dose group,middle-dose group and low -dose group of 95% ,70%EEEP have obvious inhibitory effects on ear edema, increasing capillary per-meability of skin in mice induced by dimethylbenzene and the twist re-spectively, but no significant effect on CIP, CT and ejaculation times. However, with the increase of the dose, it showed a tendency to increase CT and ejaculation times.Conclusion EEEP has significant anti-inf-la-mmatory, analgesic activities and definite effects on sexual behaviours of normal male rats .
