Retrospective observation of bovine lung phospholipid injection combined nasal continuous positive airway pressure for treating severe meconium aspiration syndrome
10.13699/j.cnki.1001-6821.2015.01.004
- VernacularTitle:牛肺磷脂注射液联合持续气道正压治疗重症胎粪吸入综合征疗效的回顾性研究
- Author:
Lin GUO
1
;
You-Ying LU
Author Information
1. 泸州医学院 附属医院 新生儿科
- Keywords:
bovine lung phospholipid injection;
newbom;
severe meconium aspiration syndrome;
nasal continuous positive airway pressure
- From:
The Chinese Journal of Clinical Pharmacology
2015;(1):11-13
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the clinical efects of bovine lung phospholipid injection ( Kelisu ) combined nasal continuous positive airway pressure ( NCPAP ) for treating severe meconium aspiration syndrome( MAS).Methods Thirty-six infants with MAS in our de-partment were selected, and divided into two groups according to whether or not to use Kelisu.Control group were given NCPAP thera-py, treatment group were treated with Kelisu combined NCPAP.After using Kelisu 4, 12, 24, 48 h, blood PaCO2, blood PaO2, blood pH, FiO2 and PEEP were observed.We also observed the time of u-sing NCPAP, the oxygen cure time, the number of cases of diverted mechanical ventilation.Results Compared with the control group, the blood PaO2, blood pH after 4,12,24,48h treatment of the treat-ment group were higher,the blood PaCO2 , FiO2 and PEEP were low-er, and the time of using NCPAP, the oxygen cure time, the number of cases of diverted mechanical ventilation were less ( P <0.05 ) . Conclusion Bovine lung phospholipid injection fcombined NCPAP for treating severe meconium aspiration syndrome has better efects and is worth clinical application.
