Clinical study of Wenyangfang in the treatment of heart failure
10.13699/j.cnki.1001-6821.2015.01.002
- VernacularTitle:温阳方治疗慢性心力衰竭的临床研究
- Author:
Cai-Yan MA
1
;
Hong TO
;
Pei-Yi XIE
;
Xiao-Ling LI
;
Jian-Hua YE
Author Information
1. 浙江省立同德医院 心内科
- Keywords:
Wenyangfang;
chronic heart failure;
clinical effect
- From:
The Chinese Journal of Clinical Pharmacology
2015;(1):5-7
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the clinical effects of Wenyang in the treatment of chronic heart failure ( CHF ) .Methods Seventy patients with CHF were recruited and randomly divided into experiment group ( n=35 ) and control group ( n=35 ) .Patients in the experiment group were treated with Wenyangfang and west medicine;patients in the control group were treated with west medicine only.All the patients were treated 1 month.After 1 month treatment, the neuroendocrine indicators and LVEF were compared between the two groups.Results After treatment of 1 month, the norepinephrine, angiotensin Ⅱ( AngⅡ) , aldosterone ( ALD ) were decreased in both experiment and control group ( P <0.05), the left ventricular ejection fraction(LVEF) was both improved in the two groups.And the experiment group was much significant than that of control group ( P <0.05 ) .The total efficacy in the experiment group was much higher than that of control group ( P <0.05 ) . Conclusion Wenyangfang combined with the medicine can significant improve the LVEF and symptom in patients with CHF.
