Comparative study of quality of Angelica ultrafine grinding and Angelica pieces
10.13699/j.cnki.1001-6821.2014.12.015
- VernacularTitle:当归超微粉碎与当归饮片质量比较研究
- Author:
Yue-Feng LI
1
;
Fu-Ju XU
;
Ze-Guo ZHANG
;
Ping-An WU
;
Feng-Lin LIU
;
Rui-Qiong WANG
;
Ling-Yun FAN
Author Information
1. 甘肃中医学院 药学院
- Keywords:
Angelica;
ultrafine grinding;
HPLC;
ferulic acid
- From:
The Chinese Journal of Clinical Pharmacology
2014;(12):1124-1126
- CountryChina
- Language:Chinese
-
Abstract:
Objective To compare the quality of Angelica ultrafine grinding and Angelica pieces.Methods Methods of extraction and chromatographic is more optimized than method in Pharmacopoeia 2010.The method of ultrasonic extraction was used for 30 min by 70%metha-nol.High performance liquid chromatography ( HPLC ) method for the chromatographic conditions: Column: Kromasil C18 column (4.6 mm × 250 mm,5μm) , flow rate:1.0 mL· min -1 , detection wavelength:316 nm, column temperature:25 ℃, mobile phase:acetonitrile-water gra-dient 0.05% phosphoric acid system.Results The content of ferulic acid of water -soluble components in Angelica was higher than that of Angelica pieces.Conclusion Ultrafine grinding Angelica can improve the dissolution of the water -soluble components of ferulic acid.
