Mechanism and clinical application status of vortioxetine
10.13699/j.cnki.1001-6821.2014.11.022
- VernacularTitle:沃泰西汀的作用机制与临床应用状况
- Author:
Lai-Hai WANG
1
;
Rui-Ling ZHANG
Author Information
1. 新乡医学院 第二附属医院 药学部
- Keywords:
vortioxetin;
antidepressant;
5 -hydroxytryptamine re -uptake inhibitor;
clinical pharmacology;
clinical evaluation;
safety
- From:
The Chinese Journal of Clinical Pharmacology
2014;(11):1048-1050
- CountryChina
- Language:Chinese
-
Abstract:
Vortioxetine is a novel antidepressant.The mechanism of the antidepressant effect is related with its enhancement of serotonergic activi-ty in the central nervous system through inhibition of the re-uptake of serotonin (5-HT).Vortioxetine is clinically applied for the treatment of major depression, safe and well tolerated.This article reviews the clinical pharmacology, clinical evaluation and safety of vortioxetin.
