Analysis on adverse drug reactions of lenalidomide
10.13699/j.cnki.1001-6821.2014.10.025
- VernacularTitle:来那度胺临床使用的不良反应调查与分析
- Author:
Ze-Ping HUANG
1
;
Chun-Yan LIU
Author Information
1. 海军总医院 门诊部
- Keywords:
lenalidomide;
adverse drug reactions;
hematological system damages;
multiple myeloma
- From:
The Chinese Journal of Clinical Pharmacology
2014;(10):952-954
- CountryChina
- Language:Chinese
-
Abstract:
Objective To analyze the adverse drug reactions (ADRs) of lenalidomide in recent 8 years.Methods Reports on ADRs of lena-lidomide included in CNKI and PubMed databases were searched and collected, and then were selected and analyzed according to age , gender, and etiology of patients, as well as dosages and signs of ADRs.Results Among the 369 cases, majority of ADRs occurred at the dosage of 25 mg? d-1 , and the incidence of ADRs on aged patients was higher than middle aged patients.About 36.81% ADRs were characterized as hema-tological system damages.Conclusion Patients treated with lenalido-mide should be paid attention to hematological system damages , especial-ly in cancer patients with decreasing systemic immunity .
