Healthy volunteers′knowledge and perception of clinical research

VernacularTitle:健康志愿者对临床研究的认知调查
Author: Yu-Dong WEI ¹ ; Li YANG ; Shuang ZHANG ; Jing-Chuan GUO ; Hai-Yan LI ; Yu-Mei SUN
Author Information

1. 北京大学护理学院
Keywords: phase I clinical study; questionnary investigation; volun-teers protection; paid
From: The Chinese Journal of Clinical Pharmacology 2014;(9):828-829,832
CountryChina
Language:Chinese
Abstract: Objective To study knowledge of healthy volunteers in-volved in Phase ⅠClinical Studies to clinical researches and related fac-tors.Methods The public awareness of research for therapeutic ad-vancements through knowledge and empowerment (PARTAKE) question-naires, designed by Duke University , were administered to 100 partici-pants in phaseⅠclinical study in Peking university third hospital.Re-sults The following perceptions were reported: research benefited our society (96.0%) , human experiment was necessary for developing new therapeutic method (91.0%), confidentiality and voluntary participating were adequately approved ( 90.0%) , all the undesirable effects were caused by the research ( 18.0%) , and volunteers would be paid for any undesirable adverse reactions completely ( 81.0%).Conclusion Re-sults suggest that the healthy volunteers have a good command of clinical research generally.They are aware of protections to participants , but they do not have a full understanding of compensation for damages .