Retrospective analysis on correlation of drug interactions and pathological factors with warfarin efficacy
10.13699/j.cnki.1001-6821.2014.09.022
- VernacularTitle:回顾性分析合并用药与病理因素等对华法林抗凝患者疗效的影响
- Author:
Qian XIANG
1
;
Heng-Hai SU
;
Guang-Yan MU
;
Ying ZHOU
;
Yi-Min CUI
Author Information
1. 北京大学 第一医院 药剂科
- Keywords:
warfarin efficacy;
adverse drug reaction;
drug interaction;
pathological factor
- From:
The Chinese Journal of Clinical Pharmacology
2014;(9):822-824
- CountryChina
- Language:Chinese
-
Abstract:
Objective To provide a scientific basis for hospitalized pa-tients receiving warfarin anticoagulant therapy.Methods Collecting 136 medication records of inpatients that have used warfarin in cardiology wards of our hospital from January 2012 to June 2013 , and analyzing the correlation of drug interactions and pathological factors with warfarin effi-cacy and adverse reaction.Results and Conclusion Moxifloxacin , acarbose , metformin and methylprednisolone are probably effect on warfa-rin treatment -related indicators.Infection and bleeding adverse effect prolonged hospitalization days.Warfarin therapy were influenced by drug interactions and pathological factors.
