Quantitative analysis on the conditions adequate for the existence of the second gas effect
10.13699/j.cnki.1001-6821.2014.09.019
- VernacularTitle:吸入麻醉第二气体效应存在条件的定量分析
- Author:
Han-Bing LIANG
1
;
Dong-Hua SHAO
;
Li-Hua HANG
;
Ti-Jun DAI
Author Information
1. 徐州医学院 数理教研室
- Keywords:
the second gas effect;
uptake rate;
conditions for existence;
quantitative analysis
- From:
The Chinese Journal of Clinical Pharmacology
2014;(9):813-815
- CountryChina
- Language:Chinese
-
Abstract:
Objective To make a quantitative analysis on the existence of the second gas effect.Methods Under the guidance of the macro-scopic theories in thermodynamics and quantitative analysis in mathematics, the second gas effect was discussed at three aspects: the conditions for the existence of the second gas effect , those for the non-existence of the second gas effect and those for the existence of the re-verse second gas effect.Results When the uptake rate of the second gas was equal to the average uptake rate of other gas mixtures , the second gas effect did not exist .When the former was less than the latter , the second gas effect existed .When the former was greater than the latter , the reverse second gas effect existed.Conclusion The existence of the second gas effect is not absolute but conditional.The key factor is the relative size of the uptake rate of the second gas and the average uptake rate of other gas mixtures in alveolar.
