Retrospective analysis of clinical efficacy of zithromax combined with Xiaoer Xiaoji Zhike oral liquid in the treatment of mycoplasma pneumonia
10.13699/j.cnki.1001-6821.2014.07.001
- VernacularTitle:回顾性分析阿奇霉素联合小儿消积止咳口服液治疗支原体肺炎的临床疗效
- Author:
Zhi-Feng SHEN
1
;
Xue-Dong RUAN
Author Information
1. 成都中医药大学 附属医院 儿科
- Keywords:
mycoplasma pneumonia;
zithromax;
humoral immunity;
Xiaoer Xiaoji Zhike oral liquid
- From:
The Chinese Journal of Clinical Pharmacology
2014;(7):563-564,574
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the clinical efficacy of zithromax combined with Xiaoer Xiaoji Zhike oral liquid in the treatment of myco-plasma pneumonia and their effects on humoral immunity function.Methods Eighty-seven patients with mycoplasma pneumonia were in-cluded in this study.Of the 87 children , 51 were treated with zithromax ( control group ) and others were treated with zithromax combined with Xiaoer Xiaoji Zhike oral liquid ( experiment group ).The clinical efficacy and serum immune index were compared between two groups after treat-ment.Results The clinical efficacy rate of experiment group (88.9%) was much higher than control group ( 70.6%) after one week treatment ( P<0.05 ).After treatment , the serum immunoglobulin M ( IgM ) and immunoglobulin A ( IgA) were significantly decreased in the two groups , with the experiment group decreasing more significantly ( P<0.05 ).The cough scores in the experiment group were significantly lower than that of the control group ( P<0.05 ).Conclusion Zithromax combined with Xiaoer Xiaoji Zhike oral liquid can significantly improve clinical efficacy and reduce the immune response in children .