Comparison and analysis of pathogen distribution and drug resistance in geriatric ward in 2012-2013
10.13699/j.cnki.1001-6821.2014.06.019
- VernacularTitle:2012-2013年老年病房病原菌分布及耐药性比较与分析
- Author:
Wei LIU
1
;
Yuan YUAN
;
Xin-Gen YUAN
Author Information
1. 北京市西城区广外医院 药剂科
- Keywords:
pathogen;
drug resistance;
antimicrobial agent;
geriatric ward
- From:
The Chinese Journal of Clinical Pharmacology
2014;(6):531-533
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the pathogens distribution and their antimicrobial resistance in geriatric ward in 2012 and 2013 , and to provide basis for clinical rational use of antimicrobial drugs.Methods The retrospective survey method was adopted.The submitted samples were inoculated with MaiKangKai tablet and blood agar plate , cultured colonies after 24 h were isolated , identified and susceptibility testing was performed.The software WHONET5.4 was used to analyze the drug sus-ceptibility results.Results Of the1485 samples, 622 pathogens were detected.The positive rate was 41.88%.There were 564 strains of gram negative bacteria , accounting for 90.68%and 58 strains of gram-posi-tive bacteria , accounting for 9.32%.Of all gram -negative bacteria , Pseudomonas aeruginosa ( PA ) accounted for 37.75% ( 94/249 ) and 44.76%( 141/315 ) in 2012 and 2013 respectively .Of all gram-posi-tive bacteria , methicillin -resistant Staphylococcus aureus ( MRSA ) accounted for 51.85% ( 14/27 ) , and 45.16% ( 14/31 ) in 2012 and 2013 respectively.Pseudomonas aeruginosa′s resistance rates to meropen-em were 27.66%and 46.81%, in 2012 and 2013 respectively , increasing by 19.15%.Resistance rates to aztreonam were 43.62% and 25.53%, decreasing by 18.09%.Conclusion Pathogens detected were mainly gram-negative bacteria.The detection rate of PA tends to increase.To strengthen the pathogen distribution and drug resistance monitoring is of great guiding significance for rational clinical use of antimicrobial agents , and reducing drug resistance rates.
