FDG-PET Scan in Patients with Pelvic Recurrence of Cervical Cancer.
- Author:
Yeon Jin PARK
1
;
Eul Ju MOON
;
Hee Hwahn CHUNG
;
Ju Won ROH
;
Sang Yoon PARK
;
Keon Wook KANG
Author Information
1. N-C-C, Research Institute and Hospital, Goyang, Korea.
- Publication Type:Original Article
- Keywords:
Cervical cancer;
PET;
Pelvic exenteration
- MeSH:
Humans;
Intestines;
Lung;
Magnetic Resonance Imaging;
Neoplasm Metastasis;
Pelvic Exenteration;
Positron-Emission Tomography;
Recurrence*;
Uterine Cervical Neoplasms*
- From:Korean Journal of Obstetrics and Gynecology
2003;46(5):991-997
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
OBJECTIVE: The purpose of this study was to investigate the clinical feasibility of FDG-PET scan in selection of patients with pelvic recurrence of cervical cancer for surgical treatment. METHODS: From Jun. 2001 to Oct. 2002, whole body FDG-PET scan findings were compared with findings of CT, MRI, and pathologic reports in 24 patients with pelvic recurrence of cervical cancer. PET scan was obtained with a GE Advance PET scanner, beginning at 60 minutes after injection of 370-555 MBq (10- 15 mCi) of 18F FDG. Regional scan was also obtained if needed. Uptake exceeding 2.5 SUV was determined as a positive finding. RESULTS: Among these 24 patients, 10 patients had metastatic lesions at pelvic lymphnodes (4), para- aortic lymphnodes (3), mediastinal lympnnodes (1), lung (4), and bone (1). Among 14 patients with no metastasis, 10 patients underwent surgical treatment but the operations were abandoned in 2 patients due to lymphnodes metastasis and pelvic peritoneal spreads that confused as normal FDG uptake of the intestines pre- operatively. Among 8 patients whom the operation was completed, 3 patients received pelvic exenteration, 2 patients received CORT, and 3 patients received LEER. CONCLUSION: FDG-PET is clinically feasible in selection of patients with pelvic recurrence of cervical cancer for surgical treatment.
