Relationship between the high sensitivity C reactive protein level and the situation of the acute cerebral infarction
- VernacularTitle:超敏C反应蛋白水平与急性脑梗死病情的相关性
- Author:
Jian-Qiong ZHENG
1
;
Nian-An YANG
Author Information
1. 湖北民族学院 附属民大医院
- Keywords:
acute cerebral infarction;
hypersensitive C reaction protein;
nervous system damage score;
correlation fac-tor with acute cereberal infarction;
turnover of acute cerebral infarction
- From:
The Chinese Journal of Clinical Pharmacology
2014;(5):391-393
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the relationship between the serum high-sensitivity C-reactive protein level and the situation of the acute cerebral infarction.Methods The trial group was made up of 151 diag-nosed patients with acute cerebral infarction in our hospital and in ac-cordance with the degree of neurological deficit score , they were divided into light , medium and heavy -duty groups.Patients in the trial group were given intravenous dextran 250 mL for 7 consecutive days , Danhong injection 250 mL for 14 days, 5%sodium bicarbonate 250 mL for 3 con-secutive days , and depending on the patient's condition , no more than 12 ,500 units of heparin were given.The control group were 151 random samples from the hospital medical center health personnel.The serum high-sensitivity C-reactive protein , D-dimer and low -density lipo-protein-C ( LDL-C) level monitoring in both groups were carried out.Then the two groups were compared.The relationship between serum high-sensitivity C-reactive protein level and severity of acute cerebral infarction was analyzed.Results The positive rate and serum levels with serum hypersensitive C -reactive protein and D-dimer in patients with acute cerebral infarction were higher than those of the control group , with statistical difference ( P<0.05 ) .Hs CRP and nervous system damage score were high positive correlation ( P<0.05 ) .D-dimer level score was positively correlated with nervous system damage ( P <0.05 ). Conclusion The high sensitivity C -reactive protein level can reflect the incidence and development of cerebral dis-ease independently , and the disease associated with prognosis and close monitoring of high sensitivity C -reactive pro-tein level on the prognosis of significance.