Pharmaco-metabonomics and its applications
- VernacularTitle:药物代谢组学及其应用
- Author:
Nan BAI
1
;
Yong-Yao LIN
;
Rui WANG
;
Ming-Jing TANG
;
Jin WANG
Author Information
1. 解放军总医院 药物临床研究中心
- Keywords:
pharmaco -metabonomics;
individualized therapy;
drug safety evaluation
- From:
The Chinese Journal of Clinical Pharmacology
2014;(4):374-376
- CountryChina
- Language:Chinese
-
Abstract:
Pharmaco-metabonomics can predict the outcome of a drug or xenobiotic intervention in an individual based on a mathematical model of pre-intervention metabolite signatures.Its main objective is to find disease-related biomarkers or biomarkers group with individual differ-ences and on behalf of individual metabolism.Pharmaco-metabonomics will play an important role in drug safety evaluation and individualized therapy.
