Clinical research of the effect of dexmedetomidine on patients undergoing abdomi-nal surgery and on quality of post-surgery recovery
- VernacularTitle:右美托咪啶用于腹部手术全身麻醉效果及术后恢复质量的临床研究
- Author:
Dong ZHAO
1
;
Ming-Tu ZHANG
Author Information
1. 金华市中心医院 麻醉科
- Keywords:
dexmedetomidine;
abdominal surgery;
general anesthesia
- From:
The Chinese Journal of Clinical Pharmacology
2014;(4):317-319
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the clinical efficacy and safety of dexmedetomidine ( DEX ) on patients undergoing abdominal surgery who received general anesthesia and on quality of post -surgery recovery.Methods Ninety-one patients who were planed for abdominal surgery with general anesthesia were randomly divided into treatment group ( n=44 ) and control group ( n=47 ) with random number table.Patients in control group were given saline 15 mL 15 min prior general anesthesia.And patients in treatment group were given DEX 0.5 μg· kg -1 and then 0.25 μg· kg -1 · h-1 in the procedure of operation.Spontaneous breath-ing, awaking time, extubation time and side effects were compared be-tween two groups.Results The VRS analgesic score in treatment group was much lower than that in control ( P<0.05 ).The incidence rate of agitation bucking in treatment group was much lower than that in control group ( P<0.05 ).But spontaneous breathing time , awaking time and extubation time showed no statistical difference between the two groups ( P>0.05).Conclusion DEX can significantly reduce the risk of de-veloping agitation , bucking and improve the general anesthesia efficacy in patients receiving abdominal surgery who underwent general anesthesia.
