Analgesic effect of fentanyl combined with propofol in the abortion
- VernacularTitle:芬太尼联合异丙酚用于人工流产的镇痛效果
- Author:
Jian-Li ZHU
1
;
Yong-Ju YE
;
Guan-Cui LAN
Author Information
1. 丽水市中医医院临床药学室
- Keywords:
abortion;
fentanyl;
propofol
- From:
The Chinese Journal of Clinical Pharmacology
2014;(4):315-316,319
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the analgesic effects of fentanyl combined with propofol compared with fentanyl alone in the abortion.Methods A total of 366 abortion patients were recruited from Aug 2010 to Aug 2013 in the outpatients department of our hospital.One hundred and sixty-seven patients were given fentanyl combined with propofol and the other 199 cases were given fentanyl only.The pain score , vaginal bleeding , the incidence of postoperative nausea vomiting and abortion syndrome were compared between the two groups.Results The analge-sic effect was better in combination group compared with fentanyl group ( P<0.05 ).The vaginal bleeding , incidence of nausea vomiting and a-bortion syndrome had no statistical significance ( P>0.05 ).Conclusion Fentanyl combined with propofol can significantly improve the analge-sic effects compared with fentanyl only in the treatment of abortion , and without increase in the risk of nausea vomiting and abortion syndrome.