Antibiotic resistance of 9005 clinic isolated bacteria in Beijing Hospital in recently 4 years
10.3969/j.issn.1001-6821.2010.01.015
- VernacularTitle:北京医院近4年9005株临床分离细菌耐药性监测结果
- Author:
Xiao-Man AI
1
;
Feng-Rong TAO
;
Tian-Zhi XUAN
;
Dong-Ke CHEN
;
Hong-Tao XU
;
Yun-Jian HU
Author Information
1. 卫生部北京医院
- Keywords:
antibiotic resistance monitor;
resistance
- From:
The Chinese Journal of Clinical Pharmacology
2010;26(1):57-63
- CountryChina
- Language:Chinese
-
Abstract:
Objective To analyze the antibiotic resisitance of clinic iso-lated bacteria in Beijing Hospital from 2005 to 2008.Methods Making antibiotic sensitivity test of total 9005 strains isolated from patients in Bei-jing Hospital from 2005 to 2008 with K-B method;analyzing the data with Whonet 5.4 system.Results The total strains of gram negative ba-cilli were more than gram positive coccus.There are 19 Penicillin non-susceptible S.pneumoniae(PRSP).As to hemolytic streptococcus,none of them was resistant to penicillin.The β-lactamase producing rate of Haemophilus influenzae was decreased from 13% in 2005 to 4.5% in 2008.During 2008.the methicillin-resistant Staphylococcus aureus (MRSA)was 76.8%and that of methicillin-resistant coagulase-nage-tire Staphylococcus(MRSCoNS)was 69.0%.Vancomycin and linezolid resistance strains did not appear.The resistance rate of Enterococcus fae-cium was higher than that of Enterococcus faecalis.The resistant rates of Enterococcus.to vancomycin and teicoplanin had increasing tendency.The detection rate of extended-spectrum beta-lactamases(ESBLs)to E. coli Was 43.0%.21.3%,52.0%and 52.6%in 4 years.The detection rates of ESBLs to Klebiella pneumonia Was 15.0% 25.9%.18.3% and 25.0%.Multi-antibiotic resistant strains of Pseudomonas aerugirlosa and Acineto-bacter appeared.Conclusion In order to study the resistance and its tendency of bacteria isolated from patients in Beijing Hospital and offer the theory to clinicalians for experienced treat.
