Analysis and evaluation of platelet bank establishment strategy from the perspective of donor loss
10.13303/j.cjbt.issn.1004-549x.2025.02.013
- VernacularTitle:从供者流失对血小板库建库策略进行分析评估
- Author:
Zheng LIU
1
;
Yamin SUN
1
;
Xin PENG
1
;
Yiqing KANG
1
;
Ziqing WANG
1
;
Jintong ZHU
1
;
Juan DU
1
;
Jianbin LI
1
Author Information
1. Henan Red Cross Blood Center, Zhengzhou 450000, China
- Publication Type:Journal Article
- Keywords:
donor loss;
platelet donor bank;
platelet transfusion refractoriness;
human leukocyte antigen;
human platelet antigen
- From:
Chinese Journal of Blood Transfusion
2025;38(2):238-243
- CountryChina
- Language:Chinese
-
Abstract:
[Objective] To analyze the loss rate of platelet donors and evaluate the strategies for establishing a platelet donor bank. [Methods] A total of 1 443 donors who joined the HLA and HPA gene donor bank for platelets in Henan Province from 2018 to 2020 were included in this study. Data on the total number of apheresis platelet donations, annual donation frequency, age at enrollment, donation habits (including the number of platelets donated per session and whether they had previously donated whole blood), and enrollment location were collected from the platelet donor information management system. Donor loss was determined based on the date of their last donation. The loss rates of different groups under various conditions were compared to assess the enrollment strategies. [Results] By the time the platelet bank was officially operational in 2022, 421 donors had been lost, resulting in an loss rate of 29% (421/1 443). By the end of 2023, the overall cumulative loss rate reached 52% (746/1 443). The loss rate was lower than the overall level in groups meeting any of the following conditions: total apheresis platelet donations exceeding 50, annual donation frequency of 10 or more, age at enrollment of 40 years or older, donation of more than a single therapeutic dose per session, or a history of whole blood donation two or more times. Additionally, loss rates varied across different enrollment locations, with higher enrollment numbers generally associated with higher loss rates. [Conclusion] Through a comprehensive analysis of donor loss, our center has adjusted its strategies for establishing the donor pool. These findings also provide valuable insights for other blood collection and supply institutions in building platelet donor banks.
