A case of chlorodifluoromethane poisoning and literature review
- Author:
GONG Zailiang
;
CHENG Xiaomiao
;
SHA Xinping
- Publication Type:Case Reports
- Keywords:
Chlorodifluoromethane;
neurological damage;
hyperbaric oxygen
- From:
China Tropical Medicine
2024;24(1):115-
- CountryChina
- Language:Chinese
-
Abstract:
We reviewed a case diagnosed with with chlorodifluoromethane poisoning (Freon-22) admitted to the Department of Nephrology, Xiangya Changde Hospitalin August, 2020, focusing on the clinical manifestations, laboratory examination, and course of treatment of patients, as well as discussing the clinical characteristics, treatment and prognosis of chlorodifluoromethane poisoning cases. The patient is a 29 years old male engaged in air conditioning maintenance work, with an acute onset. On the day of onset, the patient refilled chlorodifluoromethane poisoning refrigerant for a client's air conditioner and rested in a small car after work where he was found two hours later. At that time, the patient was experiencing impaired consciousness, vomiting and incontinence. After regaining consciousness, he presented with convulsions, dizziness, numbness of limbs and muscle aches, accompanied by a decrease in limb strength. The initial hospital examination indicated that impaired liver and kidney functionality, significantly elevated creatine kinase levels, and a little exudation in the sitting lung as shown by Chest CT, and no significant abnormalities found in the electroencephalogram (EEG) or electromyogram (EMG). Subsequent investigations revealed that the connecting pipe of the steel cylinder in the car was cracked due to high temperature, which led to the leakage of chlorodifluoromethane poisoning. After active treatment with hyperbaric oxygen, hormone, nerve nutrition and liver protection, the patient's condition improved and he was discharged from the hospital. After two-year follow-up, the patient still has mild numbness in both lower limbs. At present, there are few reports of Freon poisoning, and the clinical presentations can vary greatly, with severe cases even leading to death from poisoning. This paper summarizes and reports the clinical manifestations of a patient with chlorodifluoromethane poisoning, and reviews the related literature, with the aim to improve the clinician's understanding of the disease and make a timely and effective treatment plan.
- Full text:202503061106106395322.A case of chlorodifluoromethane poisoning and literature review.pdf
