IgA Nephropathy in Renal Allografts-Recurrence and Graft Dysfunction.
10.3349/ymj.2004.45.6.1043
- Author:
Hyeon Joo JEONG
1
;
Kyu Ha HUH
;
Yu Seun KIM
;
Soon Il KIM
Author Information
1. Department of Pathology, Yonsei University College of Medicine, Seoul, Korea. jeong10@yumc.yonsei.ac.kr
- Publication Type:Review ; Research Support, Non-U.S. Gov't
- Keywords:
IgA nephropathy;
renal transplantation;
recurrence;
histology;
proteinuria
- MeSH:
Glomerulonephritis, IGA/*physiopathology/*surgery;
Humans;
Kidney/*physiopathology;
*Kidney Transplantation;
Recurrence;
Research Support, Non-U.S. Gov't;
Transplantation, Homologous
- From:Yonsei Medical Journal
2004;45(6):1043-1048
- CountryRepublic of Korea
- Language:English
-
Abstract:
With time after transplantation, the recurrence of IgA nephropathy (IgAN) becomes a relevant cause of graft dysfunction and failure. However, only limited information has been published regarding the related clinical and histological features. In this article, we review studies on recurrent IgAN in the English literature and describe our own clinical experience. The clinical and histological features related to recurrence are still indeterminate, but features associated with graft dysfunction include proteinuria, glomerulosclerosis, mesangial proliferation, glomerular crescents and interstitial fibrosis.
