The Association between Body Mass Index and Hot Flash in Midlife Women: A Meta-analysis.
- Author:
Fatemeh SHOBEIRI
1
;
Ensiyeh JENABI
;
Jalal POOROLAJAL
;
Seyyed Mohammad Mahdi HAZAVEHEI
Author Information
- Publication Type:Meta-Analysis ; Review
- Keywords: Body mass index; Case-control studies; Cohort studies; Hot flashes; Meta-analysis
- MeSH: Body Mass Index*; Case-Control Studies; Cohort Studies; Female; Hot Flashes; Humans; Obesity; Odds Ratio; Overweight; Population Characteristics; Prospective Studies; Publication Bias
- From:Journal of Menopausal Medicine 2016;22(1):14-19
- CountryRepublic of Korea
- Language:English
- Abstract: OBJECTIVES: The association between body mass index (BMI) and hot flash risk has not been specifically clarifies yet. This meta-analysis was, therefore, conducted to estimate the association between overweight and obesity and hot flash risk. METHODS: We searched PubMed, Web of Science, and Scopus for observational studies addressing the association between BMI and hot flash until August 2015. Data were independently extracted and analyzed using 95% odds ratio (OR), and confidence intervals (CI) based on the random-effects models. RESULTS: We identified 2,244 references and conducted seven studies with 4,219 participants. The association between hot flash and overweight was estimated 1.13 (95% CI: 0.97-1.32) and that of obesity was estimated 1.79 (95% CI: 1.52-2.11). No evidence of heterogeneity and publication bias was observed. CONCLUSION: This meta-analysis demonstrated that, though not to a great extent, obesity does increase the risk of hot flash. The findings from this meta-analysis indicated that obesity is associated with an increased risk of hot flash. Further large prospective cohort studies are required to provide convincing evidence as to whether or not BMI is associated with an increased risk of hot flashes.
