Yttrium-90 resin microsphere selective internal radiation therapy on giant hepatocellular carcinoma in right lobe of liver: a case report
10.12025/j.issn.1008-6358.2025.20241512
- VernacularTitle:钇-90树脂微球选择性内放射治疗肝右叶巨块型肝癌1例报告
- Author:
Nuoya LI
1
;
Mingxing XU
1
;
Jianliang XU
1
Author Information
1. Department of Liver Surgery, the Third Affiliated Hospital, Sun Yat-sen University, Guangzhou 510000, Guangdong, China.
- Publication Type:Monographicreport:Yttrium-90microsphereinternalradiationtherapyonlivercancer
- Keywords:
Yttrium-90 resin microsphere;
selective internal radiation therapy;
giant hepatocellular carcinoma
- From:
Chinese Journal of Clinical Medicine
2025;32(1):35-40
- CountryChina
- Language:Chinese
-
Abstract:
Primary liver cancer is a common malignant tumor in China. The current main treatment methods include surgical resection, liver transplantation, interventional therapy, radiofrequency ablation, chemotherapy, targeted therapy, and immunotherapy. Yttrium-90 microsphere selective internal radiation therapy (90Y-SIRT) represents a critical treatment option for converting unresectable intermediate to advanced hepatocellular carcinoma. This report details a case of a patient with a giant hepatocellular carcinoma in the right lobe treated with 90Y resin microsphere at the Third Affiliated Hospital of Sun Yat-sen University. Post-treatment, the tumor showed significant necrosis and reduction in size, with a marked decrease in alpha fetoprotein (AFP) levels and notable improvement in clinical symptoms. The case highlights the substantial efficacy of 90Y-SIRT in controlling tumor progression and enhancing patient quality of life.