The Factors that Predict Using Mechanical Ventilation for Patients with Organophosphate Intoxication.
- Author:
Dong Chan PARK
1
;
Jung Bae PARK
;
Yun Jeong KIM
;
Soo Jeong SHIN
;
You Ho MUN
;
Sin Ryul PARK
;
Hyun Wook RYOO
;
Kang Suk SEO
;
Jae Myung CHUNG
Author Information
1. Department of Emergency Medicine, College of Medicine, The Kyungpook National University, Daegu, Korea. jbpark@kyungpook.ac.kr
- Publication Type:Original Article
- Keywords:
Organophosphate intoxication;
Cholinesterase;
APACHE II score;
Mechanical ventilation
- MeSH:
APACHE;
Cholinesterases;
Eating;
Emergencies;
Humans;
Medical Records;
Respiration, Artificial;
Retrospective Studies;
Ventilation
- From:Journal of The Korean Society of Clinical Toxicology
2010;8(2):106-112
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
PURPOSE: The purpose of this study is to investigate the factors that predict using mechanical ventilation for patients with organophosphate intoxication. METHODS: We retrospectively reviewed the medical records of 111 patients with acute organophosphate intoxication and who were treated in our emergency center from January 2000 to December 2008. We compared the toxicologic characteristics, the laboratory findings and the APACHE II scores between the Mechanical Ventilation group (MV group) and the non-Mechanical Ventilation group (the non MV group). RESULTS: Sixty three patients were in the MV group and 48 patients were in the non MV group. In the MV group, the patients had an older age (p<0.001), a larger amount of ingestion (p<0.001), a lower initial serum cholinesterase level (p=0.003), a higher APACHE II score (p<0.001) and they ingested a more toxic agent (p=0.001). There were no significant differences in gender, the type of visit and the arrival time between the MV group and the non MV group. CONCLUSION: We suggest that the patient's age, the amount of organophosphate ingestion, the toxicity of the agent, the initial serum cholinesterase level and the APACHE II score are important factors to determine if mechanical ventilation will be applied for patients with organophosphate intoxication.
