Decision-making behavior in patients with depressive disorder and its relationship with depressive and anxiety symptoms
10.11886/scjsws20240614001
- VernacularTitle:抑郁障碍患者的决策行为及其与抑郁焦虑症状的关系
- Author:
Yuxiang WANG
1
;
Luoya ZHANG
1
;
Maomao ZHANG
1
;
Juan DENG
2
;
Yanjie PENG
2
;
Xiaotong CHENG
3
;
Kezhi LIU
1
;
Wei LEI
1
;
Jing CHEN
1
Author Information
1. Affiliated Hospital of Southwest Medical University， Luzhou 646000， China
2. Southwest Medical University， Luzhou 646000， China
3. Sichuan Mental Health Center·The Third Hospital of Mianyang， Mianyang 621000， China
- Publication Type:Journal Article
- Keywords:
Depressive disorder;
Decision-making behavior;
Probability reversal learning;
Depressive and anxiety symptoms
- From:
Sichuan Mental Health
2025;38(1):22-27
- CountryChina
- Language:Chinese
-
Abstract:
BackgroundPatients with depressive disorder often exhibit impaired decision-making functions. However， the relationship between decision-making abilities and depressive and anxiety symptoms in these patients remains unclear. ObjectiveTo explore the characteristics of decision-making behavior in patients with depressive disorder， and to analyze its relationship with clinical symptoms. MethodsA total of 48 patients diagnosed with depressive disorder according to the Diagnostic and Statistical Manual of Mental Disorders， fourth edition （DSM-IV） were recruited from the Department of Psychosomatic Medicine of the Affiliated Hospital of Southwest Medical University from October 2020 to May 2023. Concurrently， 52 healthy individuals matched for age and gender were recruited from Luzhou as the control group. Beck Depression Inventory （BDI） and Beck Anxiety Inventory （BAI） were used for assessment， and decision-making behavior was evaluated using Probabilistic Reversal Learning （PRL） task. Indicators assessed included the number of trials to criterion， perseverative errors， win-stay rate and lose-shift rate. Spearman correlation analysis was used to assess the correlation between BDI and BAI scores and PRL task indicators. ResultsThe depression group showed a significantly higher lose-shift rate compared with the control group （t=3.684， P<0.01）. There were no statistically significant differences between two groups in trials to criterion， perseverative errors and win-stay rate （t=0.329， 0.132， 0.609， P>0.05）. In depression group， BDI and BAI scores were positively correlated with the win-stay rate（r=0.450， 0.398， P<0.01）. ConclusionPatients with depressive disorder are more likely to change their decision-making strategies following negative outcomes. Furthermore， the severity of depressive and anxiety symptoms is associated with a greater propensity to maintain existing decisions after receiving positive feedback. ［Funded by 2019 Joint Project of Luzhou Science and Technology Bureau-Southwest Medical University （number， 2019LZXNYDJ39］
