Homogeneity Analysis of Trace Elements and Oxygen Isotope Composition in Micro-region of Mineral Medicine Calcitum
10.13422/j.cnki.syfjx.20250464
- VernacularTitle:矿物药南寒水石微区微量元素及氧同位素组成的均一性分析
- Author:
Yuzhou ZHUO
1
Author Information
1. Medical Mineral Development Research Center，Guizhou University of Traditional Chinese Medicine，Guiyang 550025，China
- Publication Type:Journal Article
- Keywords:
calcitum;
trace elements;
rare earth elements;
isotopes;
ore-forming fluid;
Chinese herbal medicine;
quality uniformity
- From:
Chinese Journal of Experimental Traditional Medical Formulae
2025;31(7):163-171
- CountryChina
- Language:Chinese
-
Abstract:
ObjectiveTo investigate the homogeneity of trace elements and oxygen isotope composition of the calcitum by in situ micro-region analysis. MethodsSamples of calcitum were collected from Lannigou in Zhenfeng county， Guizhou province（LNG-1， LNG-2）， Taipingdong（TPD） and Zimudang（ZMD） in Xingren county， Guizhou province， Getang in Anlong county， Guizhou province（GT）， Gaolong（GL） and Badu（BD） in Tianlin county， Guangxi province， and Mingshan in Lingyun county， Guangxi province（MS）. The surface scanning of Ca， Mn and Fe elements in the microregions of TPD samples was analyzed by X-ray energy spectrum surface scanning method（EDS）. Cathodoluminescence method（CL） was used to analyze the luminescence properties of the thin slices of calcitum samples. The content and distribution uniformity of Mn， Fe and rare earth elements in the in situ microregions of LNG-1， TPD， GL and BD samples， and the δ18O and the distribution uniformity in the in situ microregions of the thin slices of LNG-2， ZMD， GT and MS samples were analyzed by laser ablation inductively coupled plasma mass spectrometry（LA-ICP-MS）. ResultsThe composition of elements and oxygen isotopes of calcitum from different origins were different. EDS analysis results showed that the Fe and Mn elements in calcitum had obvious girdle structure. The results of CL and LA-ICP-MS analysis showed that the cathode light in different regions of calcitum was red and varied in brightness， and the contents of Mn， Fe and rare earth elements were important factors affecting the brightness of the cathode light of calcitum. Regions with high content of Fe and low content of Mn had darker cathode light color， while regions with low content of Fe and high content of Mn had brighter cathode light color. When the total content of rare earth elements was>10 μg·g-1， the brightness of the cathode light would be affected， and the higher the total content of the region， the brighter the cathode light color would be. Among the samples from different origins， the calcitum tested in MS area had the largest δ18O heterogeneity， and the δ18O difference ring band with micron level was formed. Meanwhile， the δ18O content was lower in the region with darker cathode light， on the contrary， the content was higher. ConclusionThe composition of Fe， Mn， rare earth elements and δ18O of calcitum is uneven and has obvious chemical compositional ring bands， among which the calcitum in Lannigou area has good quality because of its relatively uniform chemical composition and high content of Fe and Mn elements. This study can provide experimental basis for the formulation of quality standard of calcitum.
