Effect of high-definition transcranial direct current stimulation combined with upper limb robot on upper limb dysfunction after ischemic stroke
10.3969/j.issn.1006-9771.2025.02.011
- VernacularTitle:高精度经颅直流电刺激联合上肢机器人对缺血性脑卒中上肢功能的效果
- Author:
Xiaojun WANG
1
;
Hani WANG
1
;
Hong YU
1
;
Yuanmei LI
2
;
Yuda ZHOU
1
Author Information
1. Center of Rehabilitation Evaluation and Treatment, Rehabilitation Hospital Affiliated to Zhejiang University of Chinese Medicine (Zhejiang Rehabilitation Medical Center), Hangzhou, Zhejiang 310051, China
2. Department of Neurological Rehabilitation, Rehabilitation Hospital Affiliated to Zhejiang University of Chinese Medicine (Zhejiang Rehabilitation Medical Center), Hangzhou, Zhejiang 310051, China
- Publication Type:Journal Article
- Keywords:
ischemic stroke;
upper limb;
high-definition transcranial direct current;
rehabilitation robot;
motor-evoked potential
- From:
Chinese Journal of Rehabilitation Theory and Practice
2025;31(2):218-224
- CountryChina
- Language:Chinese
-
Abstract:
ObjectiveTo investigate the effect of high-definition transcranial direct current stimulation (HD-tDCS) combined with upper limb robot on upper limb dysfunction in patients with ischemic stroke. MethodsFrom January, 2023 to March, 2024, 56 inpatients with upper limb dysfunction after ischemic stroke were selected from Zhejiang Rehabilitation Medical Center, and divided into control group (n = 28) and experimental group (n = 28) randomly. All the patients received comprehensive treatment and upper limb robot training, while the control group received sham HD-tDCS and the experimental group received HD-tDCS, for four weeks. They were assessed with Fugl-Meyer Assessment-Upper Extremities (FMA-UE), Wolf Motor Function Test (WMFT) and modified Barthel Index (MBI) before and after treatment. The cortical amplitude, cortical latency and central motor conduction time (CMCT) of transcranial magnetic stimulation motor-evoked potential (MEP) were recorded, and a correlation analysis was conducted. ResultsThe scores of FMA-UE, WMFT and MBI, and MEP cortical amplitude, cortical latency and CMCT improved in both groups after treatment (t > 3.177, P < 0.01), and they were better in the experimental group than in the control group (t > 3.610, P < 0.01). The scores of FMA-UE and WMFT negatively correlated with MEP cortical latency and CMCT, and positively correlated with MEP cortical amplitude (|r| > 0.448, P < 0.001). ConclusionHD-tDCS is effective on upper limb motor function and activities of daily living for patients with ischemic stroke, and can improve corticospinal motor conduction.
