“Hot-cold switch” in tumor microenvironment: Tesla Cell

VernacularTitle:肿瘤微环境“冷热转换”：细胞电池（Tesla Cell）
Author: LIU Yingting1 ^{1
,

2} ; HAN Weidong2 ^{1
,

2} ; JIANG Jingting1 ^{1
,

2}
Author Information

1. （1. Tumor Biological Diagnosis and Treatment Center, the Third Affiliated Hospital of Soochow University, Jiangsu Tumor Immunotherapy Engineering and Technology Research Center, Cell Therapy Research Institute, Changzhou 213003, Jiangsu, China
2. 2. Department of Bio-Therapeutic, the First Medical Center, Chinese PLA General Hospital, Beijing 100036, China)
Publication Type:Journal Article
Keywords: 细胞电池；冷肿瘤；热肿瘤；肿瘤微环境；免疫治疗
From: Chinese Journal of Cancer Biotherapy 2024;31(12):1167-1177
CountryChina
Language:Chinese
Abstract: [摘要] 免疫疗法为肿瘤治疗提供了新手段。肿瘤患者自身微环境内免疫状态的“冷”与“热”是决定患者能否响应免疫治疗的关键在素。创新性地提出“细胞电池”促进肿瘤免疫微环境“冷热转换”的概念，并从“冷肿瘤”和“热肿瘤”的概念，“冷肿瘤”和“热肿瘤”之间的转换策略，以及“细胞电池”的种类和应用对目前肿瘤免疫治疗的研究现状和进展进行综述，为肿瘤免疫治疗新疗法的构建提供坚实的理论基础。
Full text:202502281022582416620241201.pdf