Application Progress of Alginate Composite Hydrogels in Cancer Therapy
10.13748/j.cnki.issn1007-7693.20223145
- VernacularTitle:海藻酸盐复合水凝胶在癌症治疗中的应用进展
- Author:
HUANG Lili
1
;
HUANG Chengyu
2
;
XU Mingzhi
1
;
LIN Huaqing
1
Author Information
1. Guangdong Pharmaceutical University, Key Labroratory of Advanced Drug Delivery Systems of Guangdong Province, Guangzhou 510006, China
2. Guangdong Pharmaceutical University, Pharmacology Laboratory of the School of Pharmacy, Guangzhou 510006, China
- Publication Type:Journal Article
- Keywords:
hydrogel;
alginate;
cancer treatment
- From:
Chinese Journal of Modern Applied Pharmacy
2023;40(16):2295-2305
- CountryChina
- Language:Chinese
-
Abstract:
Alginate composite hydrogel is one of the research hotspots of tumor drug delivery system materials at present. Alginate hydrogel has good biocompatibility and regeneration properties. However, the natural alginate saline gel may not achieve the expected results in the body environment due to the slow degradation and instability of the gel. Alginate has found extensive application in cancer therapy through its combination with other materials and the utilization of ionic cross-linking, covalent cross-linking, and free radical polymerization to form hydrogels. Based on the composite system of alginate brine gel, this paper summarizes the structure and properties of alginate hydrogel, with a focus on recent research into alginate composite hydrogel in common cancer treatments application, summarizes the current research focus and discuss the existing problems of alginate composite hydrogel, so as to provide reference for further expanding the research of alginate composite hydrogel in clinical cancer treatment.
