Bibliometric Analysis of Off-label Drug Use in Dynamic Themes Evolution
10.13748/j.cnki.issn1007-7693.20222402
- VernacularTitle:基于文献计量的超说明书用药主题动态演化研究
- Author:
CHU Liyuan
1
;
SHEN Zefang
2
;
ZHOU Yan
1
;
LU Ruimin
2
;
WEI Xuan
2
,
3
;
YANG Tiantong
2
Author Information
1. Leshan Vocational and Technical College, Leshan 614000, China
2. Institute of Evidence Law and Forensic Science, China University of Political Science and Law, Beijing 100088, China
3. Shenzhen Hospital of Chinese Academy of Sciences(Guangming), Shenzhen 518000, China
- Publication Type:Journal Article
- Keywords:
off-label drug use;
theme evolution;
cluster analysis;
SciMAT
- From:
Chinese Journal of Modern Applied Pharmacy
2023;40(18):2576-2583
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE To study of the dynamic evolution process of the themes of off-label drug use from a macroscopic perspective, perspective is needed to reveal the overall development vein of the field, and discover research hot spots and development trends of the field. METHODS A total of 3 876 literatures published in Web of Science from 2012 to 2022 on the topic of off-label drug use were used to obtain three visual maps of overlapping map, systematic evolution map and strategic map by using SciMAT analysis, and these maps of each period were analyzed. RESULTS Over the past ten years, there had been an increasing in the number of publications, themes, and keywords on the off-label drug use, with research themes from the former period having a large impact on the latter period, with complex evolutionary pathways and increasing evolutionary themes. Roughly, 14 evolutionary paths were formed in 4 research directions:adolescents and children, treatment, off label use, and drug RCT. CONCLUSION The content and scope of research in the field of off-label drug use will be diversified and developed, with greater focus on pediatric drug use, psychiatric drug use, COVID-19, and guidelines will be paid more attention.
