Application and development of pulsed electric field ablation in the treatment of atrial fibrillation
- VernacularTitle:脉冲电场消融在房颤治疗中的应用与发展
- Author:
Zhen WANG
1
;
Ming LIANG
2
;
Jie ZHANG
3
;
Jingyang SUN
3
;
Yaling HAN
2
Author Information
1. 1. Department of Cardiology, General Hospital of Northern Theater Command, Shenyang, 110016, P. R. China 2. College of Medicine and Biological Information Engineering, Northeastern University, Shenyang, 110819, P. R. China
2. 1. Department of Cardiology, General Hospital of Northern Theater Command, Shenyang, 110016, P. R. China 3. National Key Laboratory of Frigid Zone Cardiovascular Diseases, Shenyang, 110016, P. R. China
3. Department of Cardiology, General Hospital of Northern Theater Command, Shenyang, 110016, P. R. China
- Publication Type:Journal Article
- Keywords:
Pulse electric field ablation;
atrial fibrillation;
catheter ablation;
clinical research;
treatment;
review
- From:
Chinese Journal of Clinical Thoracic and Cardiovascular Surgery
2025;32(02):270-276
- CountryChina
- Language:Chinese
-
Abstract:
With the continuous development of China's aging society and the prevalence of unhealthy lifestyles, the incidence of cardiovascular disease in China has been increasing in recent years. Among them, atrial fibrillation (AF) is the most common arrhythmia disease. In recent years, pulsed field ablation (PFA) has been continuously applied to AF treatment as a novel treatment. This paper first introduces the principle of PFA applied to AF treatment, and introduces the research progress of PFA in different directions, such as the comparison of different ablation methods, the study of physical parameters, the study of ablation area, the study of tissue specificity and clinical research. Then, the clinical prior research of PFA is discussed, including the use of simulation software to obtain the simulation effect of different parameters, the evaluation of ablation effect during animal research, and finally the current AF treatment. Various prior studies and clinical studies are summarized, and suggestions are made for the shortcomings found in the study of AF treatment and the future research direction is prospected.