Long-term outcomes of totally endoscopic minimally invasive mitral valve repair for Barlow’s disease: A retrospective cohort study
- VernacularTitle:全胸腔镜微创修复Barlow’s病长期随访结果的回顾性队列研究
- Author:
Lishan ZHONG
1
;
Yanying HUANG
2
;
Zhenzhong WANG
3
;
Shuo XIAO
3
;
Yuxin LI
4
;
Dou FANG
4
;
Qiuji WANG
5
;
Chaolong ZHANG
2
;
Huanlei HUANG
1
Author Information
1. 1. Guangdong Cardiovascular Institute, Guangdong Provincial People s Hospital, Guangdong Academy of Medical Sciences, Guangzhou, 510080, P. R. China 3. Guangdong Provincial People s Hospital, Guangdong Academy of Medical Sciences, Southern Medical University, Guangzhou, 510080, P. R. China
2. Guangdong Cardiovascular Institute, Guangdong Provincial People s Hospital, Guangdong Academy of Medical Sciences, Guangzhou, 510080, P. R. China
3. 2. South China University of Technology School of Medicine, Guangzhou, 510641, P. R. China 3. Guangdong Provincial People s Hospital, Guangdong Academy of Medical Sciences, Southern Medical University, Guangzhou, 510080, P. R. China
4. 3. Guangdong Provincial People s Hospital, Guangdong Academy of Medical Sciences, Southern Medical University, Guangzhou, 510080, P. R. China 4. Southern Medical University, Guangzhou, 510515, P. R. China
5. Guangdong Provincial People s Hospital, Guangdong Academy of Medical Sciences, Southern Medical University, Guangzhou, 510080, P. R. China
- Publication Type:Journal Article
- Keywords:
Barlow’s disease;
mitral regurgitation;
totally endoscopic minimally invasive;
median sternotomy;
mitral valve plasty
- From:
Chinese Journal of Clinical Thoracic and Cardiovascular Surgery
2025;32(01):114-120
- CountryChina
- Language:Chinese
-
Abstract:
Objective To examine the safety, efficacy and durability of totally endoscopic minimally invasive (TEMI) mitral valve repair in Barlow’s disease (BD). Methods A retrospective study was performed on patients who underwent mitral valve repair for BD from January 2010 to June 2021 in the Guangdong Provincial People’s Hospital. The patients were divided into a MS group and a TEMI group according to the surgery approaches. A comparison of the clinical data between the two groups was conducted. Results A total of 196 patients were enrolled, including 133 males and 63 females aged (43.8±14.9) years. There were 103 patients in the MS group and 93 patients in the TEMI group. No hospital death was observed. There was a higher percentage of artificial chordae implantation in the TEMI group compared to the MS group (P=0.020), but there was no statistical difference between the two groups in the other repair techniques (P>0.05). Although the total operation time between the two groups was not statistically different (P=0.265), the TEMI group had longer cardiopulmonary bypass time (P<0.001) and aortic clamp time (P<0.001), and shorter mechanical ventilation time (P<0.001) and postoperative hospitalization time (P<0.001). No statistical difference between the two groups in the adverse perioperative complications (P>0.05). The follow-up rate was 94.2% (180/191) with a mean time of 0.2-12.4 (4.0±2.4) years. Two patients in the MS group died with non-cardiac reasons during the follow-up period. The 3-year, 5-year and 10-year overall survival rates of all patients were 100.0%, 99.2%, 99.2%, respectively. Compared with the MS group, there was no statistical difference in the survival rate, recurrence rate of mitral regurgitation, reoperation rate of mitral valve or adverse cardiovascular and cerebrovascular events in the TEMI group (P＞0.05). Conclusion TEMI approach is a safe, feasible and effective approach for BD with a satisfying long-term efficacy.
