Spontaneous Acetabular Periprosthetic Fracture in a Patient Continuously Having Zoledronic Acid.
10.4055/cios.2014.6.3.358
- Author:
Saran TANTAVISUT
1
;
Aree TANAVALEE
;
Voranuch THANAKIT
;
Srihatach NGARMUKOS
;
Vajara WILAIRATANA
;
Yongsak WANGROONGSUB
Author Information
1. Department of Orthopaedics, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand. areetana@hotmail.com
- Publication Type:Case Reports
- Keywords:
Hip arthroplasty;
Fracture;
Loosening;
Zoledronic acid;
Bisphosphonate
- MeSH:
Acetabulum/*injuries/pathology/surgery;
Aged;
Arthroplasty, Replacement, Hip/*adverse effects;
Bone Density Conservation Agents/*adverse effects/pharmacology;
Bone Neoplasms/prevention & control/secondary;
Bone Remodeling/drug effects;
Breast Neoplasms/pathology;
Diphosphonates/*adverse effects/pharmacology;
Female;
Fractures, Spontaneous/chemically induced/etiology;
Hip Prosthesis;
Humans;
Imidazoles/*adverse effects/pharmacology;
Osteoarthritis, Hip/*surgery;
Periprosthetic Fractures/*chemically induced/etiology;
Prosthesis Failure;
Reoperation
- From:Clinics in Orthopedic Surgery
2014;6(3):358-360
- CountryRepublic of Korea
- Language:English
-
Abstract:
Zoledronic acid has been used for prevention of osteolytic and osteoblastic bone metastasis. This case report illustrates an undesirable consequence from prolonged usage of zoledronic acid in bone metastasis prevention. Periprosthetic acetabular fracture in a patient treated with zoledronic acid for 7 years was reported. The clinical presentation, radiographic and pathological results were described. This is a rare complication after total hip arthroplasty which should not be ignored especially in patients who received long term bisphosphonate.
