Physiologic Assessment of Coronary Artery Disease: Focus on Fractional Flow Reserve.
10.3348/kjr.2016.17.3.307
- Author:
Doyeon HWANG
1
;
Joo Myung LEE
;
Bon Kwon KOO
Author Information
1. Department of Internal Medicine and Cardiovascular Center, Seoul National University Hospital, Seoul 03080, Korea. bkkoo@snu.ac.kr
- Publication Type:Review
- Keywords:
Coronary artery disease;
Physiology;
Ischemia;
Fractional flow reserve
- MeSH:
Angiography;
Coronary Artery Disease*;
Coronary Vessels*;
Humans;
Ischemia;
Myocardial Ischemia;
Physiology
- From:Korean Journal of Radiology
2016;17(3):307-320
- CountryRepublic of Korea
- Language:English
-
Abstract:
The presence of myocardial ischemia is the most important prognostic factor in patients with ischemic heart disease. Fractional flow reserve (FFR) is a gold standard invasive method used to detect the stenosis-specific myocardial ischemia. FFR-guided revascularization strategy is superior to angiography-guided strategy. The recently developed hyperemia-free index, instantaneous wave free ratio is being actively investigated. A non-invasive FFR derived from coronary CT angiography is now used in clinical practice. Due to rapid expansion of invasive and non-invasive physiologic assessment, comprehensive understanding of the role and potential pitfalls of each modality are required for its application. In this review, we focus on the basic and clinical aspects of physiologic assessment in ischemic heart disease.
