Study on the Relationship between Gestational Overt Diabetes Mellitus and Adverse Pregnancy Outcomes
- VernacularTitle:妊娠期显性糖尿病与不良妊娠结局的研究
- Author:
Jianbin SUN
1
;
Ning YUAN
;
Xin ZHAO
;
Sixu XIN
;
Sanbao CHAI
;
Xiaomei ZHANG
Author Information
1. 北京大学国际医院内分泌科,北京 102206
- Keywords:
Gestational diabetes mellitus;
Overt diabetes mellitus;
Adverse outcomes
- From:
Journal of Practical Obstetrics and Gynecology
2024;40(10):828-832
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To explore the adverse outcomes of pregnant women with overt diabetes mellitus(ODM).Methods:A retrospective analysis was performed on 1321 pregnant women delivered in Peking Universi-ty International Hospital.Pregnant women were divided into normal blood glucose group(NGDM),gestational di-abetes mellitus group(GDM)and overt diabetes mellitus group(ODM).Maternal and neonatal adverse out-comes were compared.Results:The age,early pregnancy glycosylated hemoglobin,uric acid,triglycerides and late pregnancy glycosylated hemoglobin levels of women in ODM group were significantly higher than those in NGDM group,and the differences were statistically significant(P＜0.01).The risk of developing gestation hyper-tension(OR 6.32,P＜0.01)and cesarean section(OR 1.87,P＜0.05)in the ODM group was significantly high-er than that in the NGDM group.The rate of preterm birth(OR 2.73,P＜0.05)and macrosomia(OR 3.45,P＜0.01)in the ODM group was significantly higher than that in the NGDM group.Compared with the GDM group,the ODM group did not significantly increase the risk of hypertension,eclampsia or preeclampsia,shoulder dysto-cia,premature rupture of placenta,cesarean section,preterm birth,macrosomia,and low body mass infants(P＞0.05).Conclusion:Pregnant women with ODM increase the risk of gestational hypertension,cesarean section,preterm birth and macrosomia.Active management is needed in pregnant women with ODM.
