Baroreflex in Pain Regulation: Pathogenic Mechanism and Clinical Application

VernacularTitle:压力感受性反射在疼痛调控中的机制及临床应用
Author: Quexuan CUI ¹ ; Lu CHE ¹ ; Li XU ¹
Author Information

1. Department of Anesthesiology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100730, China
Publication Type:Journal Article
Keywords: baroreceptor reflex; autonomic nerve; pain; vagus nerve stimulation; baroreflex sensitivity
From: Medical Journal of Peking Union Medical College Hospital 2024;15(2):258-264
CountryChina
Language:Chinese
Abstract: The baroreceptor reflex is an essential mechanism for the autonomic nervous system in cardiovascular homeostasis and is closely related to pain regulation. Baroreflex sensitivity (BRS) is an indicator for quantitative evaluation of baroreflex reflex function. Pain sensitivity is negatively correlated with BRS, therefore, BRS has potential application prospects in pain risk prediction and therapeutic efficacy assessment. Vagus nerve stimulation, capable of activating the baroreceptor reflex, has been widely used in acute or chronic pain patients in recent years. This article reviews the mechanism and clinical application progress of the baroreceptor reflex in pain regulation, with the hope of providing reference for further exploring treatment to regulate baroreceptor reflex function in pain treatment.