Classification and advances in clinical research of artificial colloidal plasma substitutes
10.13303/j.cjbt.issn.1004-549x.2025.01.024
- VernacularTitle:人工胶体血浆代用品的分类及其临床研究
- Author:
Zhengyang CHANG
1
;
Ming LI
1
;
Jianpeng GAO
1
;
Jing ZHANG
1
;
Hua LYU
2
;
Licheng ZHANG
1
Author Information
1. Orthopedic Department of the Fourth Medical Center of the People's Liberation Army General Hospital, Beijing 100048China
2. School of Chemistry and Molecular Engineering, Peking University, Beijing 100871, China
- Publication Type:Journal Article
- Keywords:
shock;
plasma substitutes;
fluid resuscitation;
colloidal fluid;
endothelial glycocalyx
- From:
Chinese Journal of Blood Transfusion
2025;38(1):136-141
- CountryChina
- Language:Chinese
-
Abstract:
The number of patients with reduced blood volume due to haemorrhage, fractures, severe infections, extensive burns and tumours is increasing, and traditional blood products are no longer able to meet the increasing clinical demand. Therefore, plasma substitutes have become particularly important in fluid resuscitation, especially artificial colloidal solutions, which have a sustained volume expansion time and a good volume expansion effect, and can significantly improve the circulatory status of patients. This article aims to review the classification of artificial colloidal plasma substitutes and their research progress in clinical practice, in order provide a more rigorous, professional and standardized reference for medicine.
