Prevention and Treatment Ideas of Epileptogenesis in Children under the Perspective of Traditional Chinese Medicine and Western Medicine
10.13288/j.11-2166/r.2025.03.007
- VernacularTitle:中西医学视角下探讨儿童癫痫发生的防治思路
- Author:
Hanjiang CHEN
1
;
Ping RONG
1
;
Xilian ZHANG
1
;
Siyuan HU
1
;
Rong MA
1
Author Information
1. First Teaching Hospital of Tianjin University of Traditional Chinese Medicine/National Clinical Research Center for Chinese Medicine Acupuncture and Moxibustion，Tianjin，300181
- Publication Type:Journal Article
- Keywords:
epileptogenesis;
body constitution;
gene polymorphism;
immunoinflammation;
blood-brain barrier;
phlegm in the brain collateral
- From:
Journal of Traditional Chinese Medicine
2025;66(3):251-255
- CountryChina
- Language:Chinese
-
Abstract:
Epileptogenesis is a dynamic process of gradual progression from normal developing brain to pathological epileptic brain， which is the latent and budding stage of epilepsy. Combining the understanding of epileptogenesis in children from Western medicine and traditional Chinese medicine （TCM）， we proposed that the viewpoints of constitutional transformation， phlegm pathogen inducing epilepsy， and brain collateral damage， which correspond to key pathological mechanisms， namely gene polymorphism， immunoinflammation， and microvascular dysfunction of the blood-brain barrier， respectively. Based on these insights， strategies for prevention and treatment of epileptogenesis in children， as well as potential research directions are explored.
