Efficacy of 450 nm blue laser semiconductor treatment machine with submucosal injection of glycerol and fructose saline in bladder tumor endoscopic submucosal dissection
10.3969/j.issn.1009-8291.2025.01.009
- VernacularTitle:应用450 nm蓝激光半导体治疗机侧出光纤联合黏膜下注射甘油果糖盐水的经尿道膀胱黏膜剥脱术疗效初探(“大家泌尿网”观看手术视频)
- Author:
Fanzhuo TU
1
;
Yan HU
1
;
Xianyan CHEN
1
;
Chao MAN
1
;
Yongwei ZHAO
1
Author Information
1. Urinary Nephropathy Laser Treatment Center, Yingsheng Branch of Taian Central Hospital, Taian 271000, China
- Publication Type:Journal Article
- Keywords:
450 nm blue laser semiconductor treatment machine;
lateral optical fiber;
glycerol and fructose saline;
bladder mucosal exfoliation;
non-muscular invasive bladder cancer
- From:
Journal of Modern Urology
2025;30(1):43-47
- CountryChina
- Language:Chinese
-
Abstract:
[Objective] To explore the safety and efficacy of submucosal injection of glycerol and fructose saline in bladder tumor endoscopic submucosal dissection (BT-ESD) with a 450 nm blue laser semiconductor treatment machine in the treatment of non-muscular invasive bladder cancer (NMIBC). [Methods] Clinical data of 20 patients with bladder tumor treated with submucosal injection of glycerol and fructose saline BT-ESD via a 450 nm blue laser semiconductor treatment machine at our hospital during Nov.2023 and Apr.2024 were retrospectively analyzed.The patients included 13 males and 7 females, aged (64.95±6.89) years, tumor diameter (1.02±0.24) cm, and preoperative hemoglobin (Hb) (130.55±4.36) g/L.The operation time, Hb the next day after operation, positive rate of tumor basal biopsy, postoperative bladder irrigation time, catheter indwelling time, postoperative hospital stay, complications and recurrence rate were recorded. [Results] All operations were successful, and 28 lesions were removed.The postoperative pathological results confirmed that all cases were NMIBC, and the basal mucosa biopsies were negative.The operation time was (9.40±3.14) min, postoperative Hb (130.15±4.59) g/L, bladder irrigation time (17.70±1.34) h, catheter indwelling time 1 day, and postoperative hospital stay 1 day.There were no complications such as obturator nerve reflex, bladder perforation.There were no need for blood transfusion, no conversion to open surgery, and no secondary bleeding after operation.No tumor recurrence was found during 6-month postoperative follow up. [Conclusion] Submucosal injection of glycerol and fructose saline BT-ESD with a 450 nm blue laser semiconductor treatment machine is a safe and effective method for the treatment of NMIBC.It has advantages of whole enucleation of bladder tumor, clear basal layer, small amount of bleeding, short operation time and few complications.It can be used as a day surgery and is worthy of clinical promotion.
