Preliminary application of sacral neuromodulation in patients with benign prostatic hyperplasia complicated with underactive bladder after transurethral resection of the prostate
10.3969/j.issn.1009-8291.2025.01.008
- VernacularTitle:骶神经调控在经尿道前列腺电切术后疗效欠佳的良性前列腺增生合并膀胱活动低下症患者中的初步应用
- Author:
Ning LIU
1
;
Yan ZHANG
2
;
Tao LI
1
;
Qiang HU
1
;
Kai LU
1
;
Lei ZHANG
1
;
Jianping WU
1
;
Shuqiu CHEN
1
;
Bin XU
1
;
Ming CHEN
1
Author Information
1. Department of Urology, Zhongda Hospital Southeast University, Nanjing 210009
2. Out-patient Department, The Second Affiliated Hospital of Nanjing Medical University, Nanjing 210000, China
- Publication Type:Journal Article
- Keywords:
sacral neuromodulation;
transurethral resection of the prostate;
benign prostatic hyperplasia;
underactive bladder;
bladder outlet obstruction
- From:
Journal of Modern Urology
2025;30(1):39-42
- CountryChina
- Language:Chinese
-
Abstract:
[Objective] To evaluate the efficacy and safety of sacral neuromodulation (SNM) in the treatment of patients with benign prostatic hyperplasia (BPH) complicated with underactive bladder (UAB) who respond poorly to transurethral resection of the prostate (TURP). [Methods] A retrospective analysis was performed on 10 patients with BPH and UAB treated with TURP by the same surgeon in Zhongda Hospital Southeast University during Jan.2018 and Jan.2023.The residual urine volume was not significantly relieved after operation, and the maximum urine flow rate and urine volume per discharge were not significantly improved.All patients underwent phase I SNM, and urinary diaries were recorded before and after surgery to observe the average daily frequency of urination, volume per urination, maximum urine flow rate, and residual urine volume. [Results] The operation time was (97.6±11.2) min.During the postoperative test of 2-4 weeks, if the residual urine volume reduction by more than 50% was deemed as effective, SNM was effective in 6 patients (60.0%). Compared with preoperative results, the daily frequency of urination [(20.2±3.8) times vs. (13.2±3.2) times], volume per urination [(119.2±56.7) mL vs. (246.5±59.2) mL], maximum urine flow rate [(8.7±1.5) mL/s vs. (16.5±2.6) mL/s], and residual urine volume [(222.5±55.0) mL vs. (80.8±16.0) mL] were significantly improved, with statistical significance (P<0.05). There were no complications such as bleeding, infection, fever or pain.The 6 patients who had effective outcomes successfully completed phase II surgery, and the fistula was removed.During the follow-up of 1 year, the curative effect was stable, and there were no complications such as electrode displacement, incision infection, or pain in the irritation sites.The residual urine volume of the other 4 unsuccessful patients did not improve significantly, and the electrodes were removed and the vesicostomy tube was retained. [Conclusion] SNM is safe and effective in the treatment of BPH with UAB patients with poor curative effects after TURP.
