Comparison of the clinical efficacy of super pulse thulium laser enucleation of the prostate with "open tunnel" and holmium laser enucleation of the prostate for benign prostatic hyperplasia
10.3969/j.issn.1009-8291.2025.01.007
- VernacularTitle:“露天隧道法”经尿道前列腺超脉冲光纤铥激光剜除术与钬激光剜除术治疗良性前列腺增生的临床效果比较
- Author:
Jidong XU
1
;
Ning JIANG
1
;
Jian LI
1
;
Zhikang CAI
1
;
Jianwei LYU
1
;
Chuanyi HU
1
;
Jingcun ZHENG
1
;
Zhonglin CAI
1
;
Huiying CHEN
1
;
Yan GU
1
;
Yuning WANG
1
;
Jiasheng YAN
1
;
Zhong WANG
1
Author Information
1. Department of Urology, Shanghai Pudong Gongli Hospital (Gongli Hospital of Naval Medical University), Shanghai 200135, China
- Publication Type:Journal Article
- Keywords:
super pulse thulium laser;
holmium laser;
benign prostatic hyperplasia;
enucleation of the prostate;
"open tunnel method"
- From:
Journal of Modern Urology
2025;30(1):34-38
- CountryChina
- Language:Chinese
-
Abstract:
[Objective] To compare the clinical efficacy of super pulse thulium laser enucleation of the prostate (SPThuLEP) with "open tunnel" and transurethral holmium laser enucleation of the prostate (HoLEP) in the treatment of benign prostatic hyperplasia (BPH), in order to provide reference for the treatment options of BPH. [Methods] The clinical data of 112 BPH patients treated in our hospital during Jan.2023 and Jul.2023 were retrospectively analyzed, including 65 treated with SPThuLEP with "open tunnel" and 57 with HoLEP.The operation time, postoperative hemoglobin decrease, postoperative bladder irrigation, catheter indwelling time, hospitalization time and complications were compared between the two groups.The changes of maximum urine flow rate (Qmax), international prostate symptom score (IPSS), quality of life score (QoL), postvoid residual (PVR) and prostate-specific antigen (PSA) were compared between the two groups before operation and one month after operation. [Results] All operations were successful without conversion to open or transurethral plasmakinetic resection.The postoperative decrease of hemoglobin in SPThuLEP group was lower than that in HoLEP group [(13.12±6.72) g/L vs. (21.02±6.51) g/L], with statistical difference (P<0.05). There were no significant differences in the operation time [(63.35±15.73) min vs.(61.02±17.55) min], postoperative bladder irrigation time [(1.07±0.45) d vs. (1.06±0.36) d], catheter indwelling time [(2.98±0.56) d vs. (3.01±0.63) d] and hospitalization time [(3.63±0.61) d vs.(3.79±0.76) d] between the two groups (P>0.05). No blood transfusion, secondary bleeding or unplanned hospitalization occurred, and there were no serious complications such as transurethral electroresection syndrome (TURS), urethral stricture and urinary incontinence.One month after operation, the Qmax, IPSS, QoL, PVR and PSA of the two groups were significantly improved compared with those before operation (P<0.05), but with no statistical difference between the two groups (P>0.05). [Conclusion] SPThuLEP with "open tunnel" has comparable efficacy as HoLEP in the treatment of BPH.With advantages of small amount of bleeding and high safety, this minimally invasive technique can be widely popularized in clinical practice.
