The Secondary Amyloidosis in Rheumatic Diseases.
- Author:
Tae Jong KIM
1
;
Seung Il OH
;
Joon Sung PARK
;
Tae Yeob KIM
;
Jae Hong PARK
;
Wan Sik PARK
;
Hye Soon LEE
;
Jae Bum JUN
;
Sung Soo JUNG
;
Sang Cheol BAE
;
Dae Hyun YOO
;
Tae Hwan KIM
Author Information
1. The Hospital for Rheumatic Diseases, Hanyang University Medical Center, Seoul, Korea.
- Publication Type:Original Article
- Keywords:
Amyloidosis;
Ankylosing spondylitis;
Rheumatoid arthritis
- MeSH:
Abdominal Pain;
Amyloidosis*;
Arthritis, Rheumatoid;
Biopsy;
Cause of Death;
Colon;
Dacarbazine;
Diagnosis;
Diarrhea;
Edema;
Humans;
Kidney;
Korea;
Male;
Medical Records;
Renal Insufficiency;
Rheumatic Diseases*;
Sepsis;
Spondylitis, Ankylosing
- From:The Journal of the Korean Rheumatism Association
2003;10(1):39-44
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
OBJECTIVE: To study the clinical features and outcomes in 10 cases of secondary amyloidosis with rheumatic disease. METHODS: The secondary amyloidosis associated with rheumatic disease was studied clinically in 10 patients (4 men and 6 women), who have suspicious tissue dysfunction. The diagnosis of amyloidosis was established by histological examination of biopsy materials. We evaluated them by medical record review; clinical features at onset, organ involvement, cause of death. RESULTS: The mean age and mean duration of rheumatic disease were 52.9+/-17.27 years and 10.9+/-10.33 years respectively. The common initial clinical features were generalized edema, diarrhea and abdominal pain. The mainly involved organs were kidney and colon. Causes of death were DIC due to sepsis and renal failure. CONCLUSION: Renal and gastrointestinal symptoms are cardinal features of secondary amyloidosis with rheumatic disease in Korea.
