Glucocorticoid Receptor-beta Overexpression According to Nasal Polyp Severity: Immunohistochemical Study.
- Author:
Yong Hwi AN
1
;
Sung Lyong HONG
;
Doo Hee HAN
;
Jee Hye WEE
;
Chae Seo RHEE
;
Chul Hee LEE
;
Yang Gi MIN
Author Information
1. Department of Otorhinolaryngology, Seoul National University Hospital, Seoul, Korea. ygmin312@dreamwiz.com
- Publication Type:Original Article
- Keywords:
Caldwell-Luc operation;
Chronic maxillary sinusitis;
Endoscopic sinus surgery
- MeSH:
Facial Pain;
Follow-Up Studies;
Gingiva;
Headache;
Humans;
Hypesthesia;
Maxillary Sinus;
Nasal Polyps;
Prospective Studies;
Recurrence;
Sinusitis
- From:Journal of Rhinology
2010;17(2):102-106
- CountryRepublic of Korea
- Language:English
-
Abstract:
BACKGROUND AND OBJECTIVES: The aims of the study were to reintroduce a surgical technique for a "mini" Caldwell-Luc operation and to determine its efficacy. MATERIALS AND METHODS: A prospective study was performed in 23 patients undergoing the "mini" Caldwell-Luc operation. Improvements in clinical symptoms and endoscopic and computed tomographic (CT) findings were evaluated postoperatively over a follow-up period ranging from 6 to 21 months. All patients were surveyed for nasal symptoms (nasal obstruction, rhinorrhea, posterior nasal drip, headache, and anosmia), complications (tooth or gum pain, numbness, persistent facial pain, and facial hypo-paresthesia), and recurrence. Preoperative nasal polyps were classified by the Gaskins method, and preoperative paranasal sinusitis was graded according to the Kennedy CT staging system. RESULTS: Symptom scores were all significantly reduced postoperatively (paired t-test, p<0.05). There were no major complications specific to this technique. Among 29 maxillary sinuses that received the "mini" Caldwell-Luc operation, seven showed recurrence (24%). CONCLUSION: The "mini" Caldwell-Luc operation provides an alternative method of obtaining access to the maxillary antrum and is associated with minimal morbidity.
