A Case of Goodpasture's Syndrome.
- Author:
Sang Hee LEE
1
;
Byung Wook BANG
;
Seoung Woo LEE
;
Chul Hyun KIM
;
Seung Won LEE
;
Joon Ho SONG
;
Joon Mee KIM
;
Moon Jae KIM
Author Information
1. Division of Nephrology and Hypertension, Department of Internal Medicine, Inha University College of Medicine, Incheon, Korea. nhkimj@inha.ac.kr
- Publication Type:Case Report
- Keywords:
Goodpasture's syndrome;
Anti-glomerular basement membrane antibody;
Acute renal failure;
Pulmonary hemorrhage
- MeSH:
Acute Kidney Injury;
Adult;
Anti-Glomerular Basement Membrane Disease*;
Autoimmune Diseases;
Basement Membrane;
Biopsy;
Collagen Type IV;
Diagnosis;
Dyspnea;
Europe;
Glomerulonephritis;
Hemoptysis;
Hemorrhage;
Humans;
Immunosuppressive Agents;
Incidence;
Kidney;
Korea;
Male;
Plasma Exchange;
Renal Dialysis
- From:Korean Journal of Nephrology
2005;24(4):631-637
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Goodpasture's syndrome is an autoimmune disease characterized by rapid progressive glomerulonephritis, alveolar hemorrhage and autoantibody to the NC1 domain of the alpha 3 chain of type IV collagen (anti-glomerular basement membrane antibody). It was common in Europe with peak incidence at third decades. However, Goodpasture's syndrome was reported only three cases in Korea. We reported a case of Goodpasture's syndrome in a 34 year old male. He admitted our hospital due to dyspnea and hemoptysis. We made diagnosis by detection of Anti-GBM Ab and biopsy of kidney. He was treated with hemodialysis, plasma exchanges and immunosuppressive agents. However, his renal function was not recovered. Currently, he is receiving regular hemodialysis.