Research progress in the treatment of distal ureteral calculi with drugs
10.3969/j.issn.1009-8291.2024.12.018
- VernacularTitle:输尿管远端结石药物排石治疗研究进展
- Author:
Zhouxin LI
1
;
Lei ZHANG
1
;
Yue CHENG
2
,
3
;
Guohai XIE
4
,
5
Author Information
1. School of Medicine, Ningbo University, Ningbo 315000
2. Ningbo Clinical Medical Research Center of Urinary Diseases, Ningbo 315500
3. Urinary System Disease Innovation Technology and Diagnosis and Treatment Equipment Zhejiang Engineering Center, Ningbo 315500
4. Urinary System Disease Innovation Technology and Diagnosis and Treatment Equipment Zhejiang Engineering Center, Ningbo 315500
5. Department of Urology, The First Affiliated Hospital of Ningbo University, Ningbo 315500, China
- Publication Type:Journal Article
- Keywords:
distal ureteral calculi;
medical expulsive therapy;
α1 adrenergic receptor blocker;
β adrenergic receptor agonists;
calcium channel blockers;
prostaglandin synthetase inhibitors;
corticosteroids;
phosphodiesterase isoenzyme 5 inhibitors
- From:
Journal of Modern Urology
2024;29(12):1114-1118
- CountryChina
- Language:Chinese
-
Abstract:
Renal colic caused by ureteral stone obstruction is the main cause for emergency treatment of patients with urinary tract stones, and drug expulsion therapy plays a vital role in the treatment.This article delves into a variety of drugs, including α1 adrenergic receptor blockers, β adrenergic receptor agonists, calcium channel blockers, prostaglandin synthetase inhibitors, corticosteroids, phosphodiesterase isoenzyme 5 inhibitors, and Chinese herbal medicines, exploring their mechanisms and applications in the treatment of distal ureteral stones.Currently, α1 adrenergic receptor blockers are still preferred for the treatment of distal ureteral stones due to their significant efficacy.It is worth noting that various drugs work through different mechanisms, and combining drugs with different mechanisms is expected to improve the efficiency of stone expulsion.This method may become the mainstream choice for stone expulsion drugs in the future.This article aims to provide new perspectives and ideas for the drug treatment of urinary tract stones.
